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Direct buses › From Brussels

Brussels ▸ Prague

Prague ▸ Brussels ⇄
3.5 a dayfastest 13h10☾ 2 overnight busesFlixBus🇧🇪 Belgium → 🇨🇿 Czechia

Direct buses · no change

BrusselsLeuvenHasseltMaastrichtAachenColognePrague· 717 km as the crow flies
  • 07:35 → 20:45
    FlixBus N870
    Brussels-North train station → Prague (Central Bus Station Florenc) · via Maastricht, Cologne, Frankfurt, Nuremberg
    13h104 stops
    Runs: Only Sat 7 Novthe open data has only these datesBook on FlixBus ↗
  • 07:50 → 21:00
    FlixBus N870
    Brussels-North train station → Prague (Central Bus Station Florenc) · via Maastricht, Cologne, Frankfurt, Nuremberg
    13h104 stops
    Runs: Only Mon 9 Novthe open data has only these datesBook on FlixBus ↗
  • 08:13 → 21:23
    FlixBus N870
    Brussels-North train station → Prague (Central Bus Station Florenc) · via Maastricht, Cologne, Frankfurt, Nuremberg
    13h104 stops
    Runs: Only Sun 8 Novthe open data has only these datesBook on FlixBus ↗
  • 08:20 → 21:30
    FlixBus N870
    Brussels-North train station → Prague (Central Bus Station Florenc) · via Maastricht, Cologne, Frankfurt, Nuremberg
    13h104 stops
    Runs: Tue to Fri (some weeks)Book on FlixBus ↗
  • 09:20 → 22:30
    FlixBus N870
    Brussels-North train station → Prague (Central Bus Station Florenc) · via Maastricht, Cologne, Frankfurt, Nuremberg
    13h104 stops
    Runs: Only Sun 18 Octthe open data has only these datesBook on FlixBus ↗
  • 09:40 → 22:50
    FlixBus N870
    Brussels-North train station → Prague (Central Bus Station Florenc) · via Maastricht, Cologne, Frankfurt, Nuremberg
    13h104 stops
    Runs: Mon, Sat (some weeks)Book on FlixBus ↗
  • 10:25 → 00:45+1
    FlixBus N1310
    Brussels-North train station → Prague (Main Railway Station) · via Aachen, Coblenz, Bingen, Mainz…
    14h208 stops
    Runs: DailyBook on FlixBus ↗
  • 16:15 → 06:55+1
    FlixBus N84 ☾ Overnight
    Brussels South (Gare du Midi) → Prague (Central Bus Station Florenc) · via Leuven, Hasselt, Maastricht, Aachen…
    14h4010 stops
    Runs: DailyThe night the clocks change (Sat 24 Oct: 16:15 → 05:55+1)Book on FlixBus ↗
  • 22:30 → 13:30+1
    FlixBus N84 ☾ Overnight
    Brussels South (Gare du Midi) → Prague (Central Bus Station Florenc) · via Leuven, Hasselt, Maastricht, Aachen…
    15h009 stops
    Runs: Daily until Sun 1 NovThe night the clocks change (Sat 24 Oct: 22:30 → 12:30+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026) and FlixBus UK (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Brussels to Prague?

Yes. 3.5 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Brussels to Prague?

The fastest takes 13h10; the slowest 15h00, for 717 km as the crow flies.

When do the buses leave?

The earliest leaves at 07:35 and the latest at 22:30, local time in Brussels. Not every bus runs every day: pick a date above.

Is there a night bus from Brussels to Prague?

Yes: 2 overnight departures in the timetable, for example 16:15 arriving 06:55 the next morning.

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