Düsseldorf to Milan bus: 2.9 a day, fastest 13h05

2.9 a dayfastest 13h05☾ 2 overnight busesFlixBus🇩🇪 Germany → 🇮🇹 Italy

Direct buses · no change

DüsseldorfLeverkusenCologneBonnSaarbrückenStrasbourgMilan· 665 km as the crow flies

03:45 → 16:50
FlixBus N487
Düsseldorf central bus station → Milan (Lampugnano bus station) · via Cologne, Frankfurt, Mannheim, Karlsruhe…
13h055 stops
Runs: DailyThe night the clocks change (Sun 25 Oct: 02:45 → 15:50)Book on FlixBus ↗
17:25 → 07:10⁺¹
FlixBus N177 ☾ Overnight
Düsseldorf central bus station → Milan (Lampugnano bus station) · via Cologne, Mannheim, Heidelberg, Karlsruhe…
13h459 stops
Runs: DailyThe night the clocks change (Sat 24 Oct: 17:25 → 06:10+1)Book on FlixBus ↗
21:40 → 13:20⁺¹
FlixBus N11 ☾ Overnight
Düsseldorf central bus station → Milan (Lampugnano bus station) · via Leverkusen, Cologne, Bonn, Saarbrücken…
15h409 stops
Runs: Wed to Sun (some weeks)The night the clocks change (Sat 24 Oct: 21:40 → 12:20+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Bus, train or plane

Fastest door to door: the plane (4h20). The bus takes 9h34 longer.

Bus · fastest direct13h54

To Düsseldorf central bus station12 min
At the stop before departure15 min
FlixBus N48713h05
From Milan (Lampugnano bus station)22 min

Plane · nonstop DUS to LIN4h20

To Düsseldorf (DUS)25 min
Check-in & security1h30
Flight DUS to LIN1h40
Landing to exit20 min
From LIN25 min

City centre to city centre. Getting to stops, stations and airports: typical public-transport times (estimates). Bus: be at the stop 15 min before. Plane: check-in and security 1h30 before, then getting out after landing; flight time typical for the distance.

Train instead?

No direct train from Düsseldorf to Milan in pickthetrain's timetables: the bus is the no-change way.

Where Düsseldorf goes by direct train ↗

Flying instead?

4 airlines fly Düsseldorf to Milan nonstop. Book on the airline's own site:

EurowingsDUS→LIN · DUS→MXP · DUS→BGYBook direct ↗
ITA AirwaysDUS→LINBook direct ↗
RyanairCGN→BGYBook direct ↗
easyJetDUS→MXPBook direct ↗

Compare on picktheflight ↗

Quick answers

Is there a direct bus from Düsseldorf to Milan?

Yes. 2.9 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Düsseldorf to Milan?

The fastest takes 13h05; the slowest 15h40, for 665 km as the crow flies.

When do the buses leave?

The earliest leaves at 03:45 and the latest at 21:40, local time in Düsseldorf. Not every bus runs every day: pick a date above.

Is there a night bus from Düsseldorf to Milan?

Yes: 2 overnight departures in the timetable, for example 17:25 arriving 07:10 the next morning.

Düsseldorf ▸ Milan

Direct buses · no change

Quick answers

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