Frankfurt ▸ Plzeň
Plzeň ▸ Frankfurt ⇄1 a dayfastest 6h25FlixBus🇩🇪 Germany → 🇨🇿 Czechia
Direct buses · no change
FrankfurtWertheimWürzburgNurembergPlzeň· 338 km as the crow flies
- 11:15 → 17:40FlixBus 084Frankfurt central train station → Plzeň (central bus station) · via Wertheim, Würzburg, Nuremberg6h253 stopsRuns: DailyBook on FlixBus ↗
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Frankfurt to Plzeň?
Yes. 1 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Frankfurt to Plzeň?
The fastest takes 6h25; the slowest 6h25, for 338 km as the crow flies.
Is there a night bus from Frankfurt to Plzeň?
Not an overnight one: every bus here travels by day or evening.