Frankfurt ▸ Rome
Rome ▸ Frankfurt ⇄1 a dayfastest 20h05☾ 1 overnight busFlixBus🇩🇪 Germany → 🇮🇹 Italy
Direct buses · no change
FrankfurtMannheimKarlsruheStuttgartUlmBregenzRome· 961 km as the crow flies
- 17:45 → 13:50+1FlixBus N77 ☾ OvernightFrankfurt central train station → Rome Tiburtina Bus station · via Mannheim, Karlsruhe, Stuttgart, Ulm…20h058 stops
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Frankfurt to Rome?
Yes. 1 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Frankfurt to Rome?
The fastest takes 20h05; the slowest 20h05, for 961 km as the crow flies.
Is there a night bus from Frankfurt to Rome?
Yes: 1 overnight departure in the timetable, for example 17:45 arriving 13:50 the next morning.