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Direct buses › From Karlsruhe

Karlsruhe ▸ Ancona

Ancona ▸ Karlsruhe ⇄
1 a dayfastest 14h35☾ 1 overnight busFlixBus🇩🇪 Germany → 🇮🇹 Italy

Direct buses · no change

KarlsruheStuttgartUlmMunichBolognaRiminiAncona· 717 km as the crow flies
  • 17:05 → 07:40+1
    FlixBus N422 ☾ Overnight
    Karlsruhe central train station → Ancona · via Stuttgart, Ulm, Munich, Bologna…
    14h355 stops
    Runs: DailyThe night the clocks change (Sat 24 Oct: 17:05 → 06:40+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Karlsruhe to Ancona?

Yes. 1 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Karlsruhe to Ancona?

The fastest takes 14h35; the slowest 14h35, for 717 km as the crow flies.

Is there a night bus from Karlsruhe to Ancona?

Yes: 1 overnight departure in the timetable, for example 17:05 arriving 07:40 the next morning.

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