Karlsruhe to Brussels bus: 1.2 a day, fastest 7h30

1.2 a dayfastest 7h30☾ 1 overnight busFlixBus🇩🇪 Germany → 🇧🇪 Belgium

Direct buses · no change

KarlsruheZweibrückenSaarbrückenMerzigLuxembourgNamurBrussels· 355 km as the crow flies

10:45 → 18:15
FlixBus 1929
Karlsruhe central train station → Brussels-North train station · via Zweibrücken, Saarbrücken, Merzig, Luxembourg…
7h305 stops
Runs: Sun (some weeks)The night the clocks change (Sun 25 Oct: 09:45 → 17:15)Book on FlixBus ↗
23:10 → 06:45⁺¹
FlixBus N136 ☾ Overnight
Karlsruhe central train station → Brussels-North train station · via Strasbourg, Metz, Luxembourg
7h353 stops
Runs: DailyThe night the clocks change (Sat 24 Oct: 23:10 → 05:45+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Bus, train or plane

No direct train and no nonstop flight: the bus is the only no-change way

Bus · fastest direct8h12

To Karlsruhe central train station14 min
At the stop before departure15 min
FlixBus 19297h30
From Brussels-North train station13 min

City centre to city centre. Getting to stops, stations and airports: typical public-transport times (estimates). Bus: be at the stop 15 min before. Plane: check-in and security 1h30 before, then getting out after landing; flight time typical for the distance.

Train instead?

No direct train from Karlsruhe to Brussels in pickthetrain's timetables: the bus is the no-change way.

Where Karlsruhe goes by direct train ↗

Flying instead?

Nothing flies Karlsruhe to Brussels nonstop in picktheflight's airline data.

Check flights on picktheflight ↗

Quick answers

Is there a direct bus from Karlsruhe to Brussels?

Yes. 1.2 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Karlsruhe to Brussels?

The fastest takes 7h30; the slowest 7h35, for 355 km as the crow flies.

When do the buses leave?

The earliest leaves at 10:45 and the latest at 23:10, local time in Karlsruhe. Not every bus runs every day: pick a date above.

Is there a night bus from Karlsruhe to Brussels?

Yes: 1 overnight departure in the timetable, for example 23:10 arriving 06:45 the next morning.

Karlsruhe ▸ Brussels

Direct buses · no change

Quick answers

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