Lucerne to Milan bus: 3.2 a day, fastest 3h20

3.2 a dayfastest 3h20FlixBus🇨🇭 Switzerland → 🇮🇹 Italy

Direct buses · no change

LucerneLuganoComoMilan· 189 km as the crow flies

01:30 → 04:50
FlixBus N401
Luzern (Landenberg) → Milan (Lampugnano bus station)
3h20nonstop
Runs: DailyBook on FlixBus ↗
07:15 → 10:40
FlixBus N846
Luzern (Landenberg) → Milan (Lampugnano bus station)
3h25nonstop
Runs: Mon, Fri, Sat, SunBook on FlixBus ↗
10:45 → 15:05
FlixBus 1524
Luzern (Landenberg) → Milan (Lampugnano bus station) · via Lugano, Como
4h202 stops
Runs: Daily except TueBook on FlixBus ↗
13:10 → 16:50
FlixBus 439
Luzern (Landenberg) → Milan (Lampugnano bus station)
3h40nonstop
Runs: Mon, Tue, Fri, Sat, Sun (some weeks)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 25 Oct 2026). Checked Mon 26 Oct 2026; they cover 26 Oct to 22 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Bus, train or plane

Fastest door to door: the train (3h46). The bus takes 22 min longer.

Bus · fastest direct4h08

To Luzern (Landenberg)11 min
At the stop before departure15 min
FlixBus N4013h20
From Milan (Lampugnano bus station)22 min

Train · fastest direct3h46

To Luzern3 min
Before departure10 min
EC 1733h32
From Milano Centrale1 min

Plane · nonstop ZRH to MXP4h50

To Zurich (ZRH)1h05
Check-in & security1h30
Flight ZRH to MXP1h00
Landing to exit20 min
From MXP55 min

City centre to city centre. Getting to stops, stations and airports: typical public-transport times (estimates). Bus: be at the stop 15 min before. Plane: check-in and security 1h30 before, then getting out after landing; flight time typical for the distance. Train: pickthetrain's door-to-door time.

Train instead?

1 a daydirect trains, fastest 3h32

SBB / Trenitalia. No change of train, from the operators' official timetables.

See the trains on pickthetrain ↗

Flying instead?

2 airlines fly Lucerne to Milan nonstop. Book on the airline's own site:

Ethiopian AirlinesZRH→MXPBook direct ↗
Swiss International Air LinesZRH→MXPBook direct ↗

Compare on picktheflight ↗

Quick answers

Is there a direct bus from Lucerne to Milan?

Yes. 3.2 a day on average, with FlixBus, no change of bus (26 Oct to 22 Nov 2026).

How long is the bus from Lucerne to Milan?

The fastest takes 3h20; the slowest 4h20, for 189 km as the crow flies.

When do the buses leave?

The earliest leaves at 01:30 and the latest at 13:10, local time in Lucerne. Not every bus runs every day: pick a date above.

Is there a night bus from Lucerne to Milan?

Not an overnight one: every bus here travels by day or evening.

Lucerne ▸ Milan

Direct buses · no change

Quick answers

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