Lyon to Brussels bus: 2.5 a day, fastest 9h40

2.5 a dayfastest 9h40☾ 3 overnight busesBlaBlaCar Bus, FlixBus🇫🇷 France → 🇧🇪 Belgium

Direct buses · no change

LyonChalon-sur-SaôneDijonNancyMetzLuxembourgBrussels· 568 km as the crow flies

08:30 → 19:55
BlaBlaCar Bus
Lyon - Gerland Bus Station → Brussels - North Train Station · via Paris, Lille
11h252 stops
Runs: Daily except TueBook on BlaBlaCar Bus ↗
21:10 → 08:00⁺¹
BlaBlaCar Bus ☾ Overnight
Lyon - Gerland Bus Station → Brussels - Midi Train Station · via Chalon-sur-Saône, Dijon, Nancy, Metz…
10h505 stops
Runs: Mon, Fri, Sat, SunThe night the clocks change (Sat 24 Oct: 21:10 → 07:00+1)Book on BlaBlaCar Bus ↗
21:25 → 08:15⁺¹
FlixBus N769 ☾ Overnight
Lyon (Gerland Bus Station) → Brussels South (Gare du Midi) · via Paris, Mitry-Mory, Lille
10h503 stops
Runs: DailyThe night the clocks change (Sat 24 Oct: 21:25 → 07:15+1)Book on FlixBus ↗
22:45 → 08:25⁺¹
BlaBlaCar Bus ☾ Overnight
Lyon - Gerland Bus Station → Brussels - Midi Train Station · via Chalon-sur-Saône, Dijon, Luxembourg
9h403 stops
Runs: Only Sun 25 Octthe open data has only these datesBook on BlaBlaCar Bus ↗

Local times at each stop. Times from official open data: BlaBlaCar Bus (file of 18 Oct 2026) and FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. Contains BlaBlaCar Bus timetable data (transport.data.gouv.fr), ODbL 1.0. How we build this.

Bus, train or plane

☾ Overnight: leave 22:45, arrive 08:25

The train is 6h33 quicker door to door, but the night bus spends your night on the road instead of a day.

Bus · fastest direct10h27

To Lyon - Gerland Bus Station17 min
At the stop before departure15 min
BlaBlaCar Bus9h40
From Brussels - Midi Train Station15 min

Train · fastest direct3h54

Before departure10 min
001B3h43
From Brussel-Zuid1 min

Plane · nonstop LYS to BRU4h45

To Lyon–Saint-Exupéry (LYS)50 min
Check-in & security1h30
Flight LYS to BRU1h30
Landing to exit20 min
From BRU35 min

City centre to city centre. Getting to stops, stations and airports: typical public-transport times (estimates). Bus: be at the stop 15 min before. Plane: check-in and security 1h30 before, then getting out after landing; flight time typical for the distance. Train: pickthetrain's door-to-door time.

Train instead?

5.9 a daydirect trains, fastest 3h43

Société Nationale des Chemins de fer Français. No change of train, from the operators' official timetables.

See the trains on pickthetrain ↗

Flying instead?

1 airline fly Lyon to Brussels nonstop. Book on the airline's own site:

Brussels AirlinesLYS→BRUBook direct ↗

Compare on picktheflight ↗

Quick answers

Is there a direct bus from Lyon to Brussels?

Yes. 2.5 a day on average, with BlaBlaCar Bus and FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Lyon to Brussels?

The fastest takes 9h40; the slowest 11h25, for 568 km as the crow flies.

When do the buses leave?

The earliest leaves at 08:30 and the latest at 22:45, local time in Lyon. Not every bus runs every day: pick a date above.

Is there a night bus from Lyon to Brussels?

Yes: 3 overnight departures in the timetable, for example 21:10 arriving 08:00 the next morning.

Lyon ▸ Brussels

Direct buses · no change

Quick answers

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