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Direct buses › From Lyon

Lyon ▸ Madrid

Madrid ▸ Lyon ⇄
3.1 a dayfastest 16h40☾ 5 overnight busesBlaBlaCar Bus, FlixBus🇫🇷 France → 🇪🇸 Spain

Direct buses · no change

LyonClermont-FerrandBordeauxBayonneAngletHendayeMadrid· 912 km as the crow flies
  • 16:00 → 08:40+1
    FlixBus N748 ☾ Overnight
    Lyon (Gerland Bus Station) → Madrid (South Bus Station) · via Nîmes, Montpellier, Toulouse, Vielha…
    16h405 stops
    Runs: DailyThe night the clocks change (Sat 24 Oct: 16:00 → 07:40+1)Book on FlixBus ↗
  • 16:30 → 09:10+1
    BlaBlaCar Bus ☾ Overnight
    Lyon - Gerland Bus Station → Madrid - South Station · via Nîmes, Montpellier, Toulouse, Zaragoza
    16h405 stops
    Runs: Only Sun 25 Octthe open data has only these datesBook on BlaBlaCar Bus ↗
  • 16:30 → 09:55+1
    BlaBlaCar Bus ☾ Overnight
    Lyon - Gerland Bus Station → Madrid - South Station · via Nîmes, Montpellier, Toulouse, Zaragoza
    17h255 stops
    Runs: Mon, Thu, Fri, Sat, SunThe night the clocks change (Sat 24 Oct: 16:30 → 08:55+1)Book on BlaBlaCar Bus ↗
  • 20:55 → 14:05+1
    BlaBlaCar Bus ☾ Overnight
    Lyon - Gerland Bus Station → Madrid - South Station · via Nîmes, Montpellier, Perpignan, Barcelona…
    17h106 stops
    Runs: Wed, Fri, Sun (some weeks)Book on BlaBlaCar Bus ↗
  • 21:50 → 15:35+1
    FlixBus N1149 ☾ Overnight
    Lyon (Gerland Bus Station) → Madrid (South Bus Station) · via Clermont-Ferrand, Bordeaux, Bayonne, Anglet…
    17h458 stops
    Runs: DailyThe night the clocks change (Sat 24 Oct: 21:50 → 14:35+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: BlaBlaCar Bus (file of 18 Oct 2026) and FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. Contains BlaBlaCar Bus timetable data (transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Lyon to Madrid?

Yes. 3.1 a day on average, with BlaBlaCar Bus and FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Lyon to Madrid?

The fastest takes 16h40; the slowest 17h45, for 912 km as the crow flies.

When do the buses leave?

The earliest leaves at 16:00 and the latest at 21:50, local time in Lyon. Not every bus runs every day: pick a date above.

Is there a night bus from Lyon to Madrid?

Yes: 5 overnight departures in the timetable, for example 16:00 arriving 08:40 the next morning.

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