Niagara Falls ▸ Ithaca
Ithaca ▸ Niagara Falls ⇄1.6 a dayfastest 5h30☾ 1 overnight busFlixBus🇨🇦 Canada → 🇺🇸 United States
Direct buses · no change
Niagara FallsNiagara FallsBuffaloCheektowagaRochesterIthaca· 222 km as the crow flies
- 01:45 → 07:15FlixBus N2687 ☾ OvernightNiagara Falls Canada (Table Rock) → Ithaca · via Niagara Falls, Buffalo, Cheektowaga, Rochester5h304 stopsRuns: Mon, Tue, Wed, Sat, SunThe night the clocks change (Sun 1 Nov: 01:45 → 06:15)Book on FlixBus ↗
- 10:55 → 16:30FlixBus 2685Niagara Falls Canada (Rapidsview) → Ithaca · via Niagara Falls, Buffalo, Cheektowaga, Rochester5h354 stopsRuns: Daily except TueBook on FlixBus ↗
Local times at each stop. Times from official open data: FlixBus / Greyhound (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. How we build this.
Quick answers
Is there a direct bus from Niagara Falls to Ithaca?
Yes. 1.6 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Niagara Falls to Ithaca?
The fastest takes 5h30; the slowest 5h35, for 222 km as the crow flies.
When do the buses leave?
The earliest leaves at 01:45 and the latest at 10:55, local time in Niagara Falls. Not every bus runs every day: pick a date above.
Is there a night bus from Niagara Falls to Ithaca?
Yes: 1 overnight departure in the timetable, for example 01:45 arriving 07:15.