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Nijmegen ▸ Brussels

Brussels ▸ Nijmegen ⇄
1.7 a dayfastest 3h05FlixBus🇳🇱 Netherlands → 🇧🇪 Belgium

Direct buses · no change

NijmegenEindhovenAntwerpBrussels· 152 km as the crow flies
  • 05:20 → 08:50
    FlixBus N81
    Nijmegen Centraal Station (Tunnelweg) → Brussels-North train station · via Eindhoven, Antwerp
    3h302 stops
    Runs: DailyThe night the clocks change (Sun 25 Oct: 04:20 → 07:50)Book on FlixBus ↗
  • 11:40 → 14:45
    FlixBus 822
    Nijmegen Centraal Station (Tunnelweg) → Brussels-North train station · via Eindhoven
    3h051 stop
    Runs: Wed to SunBook on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Nijmegen to Brussels?

Yes. 1.7 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Nijmegen to Brussels?

The fastest takes 3h05; the slowest 3h30, for 152 km as the crow flies.

When do the buses leave?

The earliest leaves at 05:20 and the latest at 11:40, local time in Nijmegen. Not every bus runs every day: pick a date above.

Is there a night bus from Nijmegen to Brussels?

Not an overnight one: every bus here travels by day or evening.