Niš ▸ Istanbul
Istanbul ▸ Niš ⇄4 a weekfastest 10h25☾ 1 overnight busFlixBus🇷🇸 Serbia → 🇹🇷 Türkiye
Direct buses · no change
NišBela PalankaPirotIstanbul· 635 km as the crow flies
- 00:00 → 12:25FlixBus N1920 ☾ OvernightNiš AS → İstanbul Esenler bus station · via Bela Palanka, Pirot10h252 stopsRuns: Mon, Fri, Sat, Sun (some weeks)The night the clocks change (Sun 18 Oct: 00:00 → 11:25; Mon 19 Oct: 00:00 → 11:25; Thu 22 Oct: 00:00 → 11:25; Fri 23 Oct: 00:00 → 11:25; Sat 24 Oct: 00:00 → 11:25; Sun 25 Oct: 00:00 → 11:25)Book on FlixBus ↗
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026) and FlixBus Türkiye (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Niš to Istanbul?
Yes. 4 a week on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Niš to Istanbul?
The fastest takes 10h25; the slowest 10h25, for 635 km as the crow flies.
Is there a night bus from Niš to Istanbul?
Yes: 1 overnight departure in the timetable, for example 00:00 arriving 12:25.