Plzeň ▸ Karlsruhe
Karlsruhe ▸ Plzeň ⇄1.8 a dayfastest 6h40☾ 1 overnight busFlixBus🇨🇿 Czechia → 🇩🇪 Germany
Direct buses · no change
PlzeňNurembergHeilbronnStuttgartKarlsruhe· 369 km as the crow flies
- 16:40 → 23:50FlixBus N1315Plzeň (central bus station) → Karlsruhe central train station · via Nuremberg, Heilbronn, Stuttgart7h107 stopsRuns: DailyBook on FlixBus ↗
- 23:55 → 06:35+1FlixBus N168 ☾ OvernightPlzeň (central bus station) → Karlsruhe central train station · via Nuremberg, Heilbronn, Stuttgart6h406 stopsRuns: Thu to Sun (some weeks)The night the clocks change (Sat 24 Oct: 23:55 → 05:35+1)Book on FlixBus ↗
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Plzeň to Karlsruhe?
Yes. 1.8 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Plzeň to Karlsruhe?
The fastest takes 6h40; the slowest 7h10, for 369 km as the crow flies.
When do the buses leave?
The earliest leaves at 16:40 and the latest at 23:55, local time in Plzeň. Not every bus runs every day: pick a date above.
Is there a night bus from Plzeň to Karlsruhe?
Yes: 1 overnight departure in the timetable, for example 23:55 arriving 06:35 the next morning.