Prague ▸ Düsseldorf
Düsseldorf ▸ Prague ⇄3.6 a dayfastest 10h45☾ 1 overnight busFlixBus🇨🇿 Czechia → 🇩🇪 Germany
Direct buses · no change
PragueDresdenChemnitzGeraJenaErfurtDüsseldorf· 553 km as the crow flies
- 08:30 → 20:35FlixBus 020Prague (Central Bus Station Florenc) → Düsseldorf central bus station · via Dresden, Chemnitz, Gera, Jena…12h059 stopsRuns: Mon, Thu, Fri, Sat, Sun (some weeks)Book on FlixBus ↗
- 08:50 → 21:55FlixBus 084Prague (Central Bus Station Florenc) → Düsseldorf central bus station · via Nuremberg, Erlangen, Würzburg, Frankfurt…13h058 stopsRuns: Daily until Sat 14 Nov, not Tue 10 Nov, Wed 11 Nov, Thu 12 NovBook on FlixBus ↗
- 10:30 → 22:40FlixBus 084Prague (Central Bus Station Florenc) → Düsseldorf central bus station · via Plzeň, Nuremberg, Würzburg, Wertheim…12h108 stopsRuns: DailyBook on FlixBus ↗
- 20:00 → 06:45+1FlixBus N23 ☾ OvernightPrague (Central Bus Station Florenc) → Düsseldorf central bus station · via Dresden, Leipzig, Halle, Dortmund…10h456 stopsRuns: Wed to Sun (some weeks)The night the clocks change (Sat 24 Oct: 20:00 → 05:45+1)Book on FlixBus ↗
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Prague to Düsseldorf?
Yes. 3.6 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Prague to Düsseldorf?
The fastest takes 10h45; the slowest 13h05, for 553 km as the crow flies.
When do the buses leave?
The earliest leaves at 08:30 and the latest at 20:00, local time in Prague. Not every bus runs every day: pick a date above.
Is there a night bus from Prague to Düsseldorf?
Yes: 1 overnight departure in the timetable, for example 20:00 arriving 06:45 the next morning.