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Prague ▸ Florence

Florence ▸ Prague ⇄
1.9 a dayfastest 15h10☾ 2 overnight busesFlixBus🇨🇿 Czechia → 🇮🇹 Italy

Direct buses · no change

PragueViennaGrazKlagenfurtUdinePortogruaroFlorence· 742 km as the crow flies
  • 17:45 → 11:20+1
    FlixBus N1533 ☾ Overnight
    Prague (Main Railway Station) → Florence (Villa Costanza) · via Vienna, Graz, Klagenfurt, Udine…
    17h359 stops
    Runs: DailyThe night the clocks change (Sat 24 Oct: 17:45 → 10:20+1)Book on FlixBus ↗
  • 21:25 → 12:35+1
    FlixBus N538 ☾ Overnight
    Prague (Central Bus Station Florenc) → Florence (Villa Costanza) · via Regensburg, Freising, Innsbruck, Bolzano…
    15h107 stops
    Runs: DailyThe night the clocks change (Sat 24 Oct: 21:25 → 11:35+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Prague to Florence?

Yes. 1.9 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Prague to Florence?

The fastest takes 15h10; the slowest 17h35, for 742 km as the crow flies.

When do the buses leave?

The earliest leaves at 17:45 and the latest at 21:25, local time in Prague. Not every bus runs every day: pick a date above.

Is there a night bus from Prague to Florence?

Yes: 2 overnight departures in the timetable, for example 17:45 arriving 11:20 the next morning.

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