Prague ▸ Heilbronn
Heilbronn ▸ Prague ⇄2.5 a dayfastest 6h20☾ 1 overnight busFlixBus🇨🇿 Czechia → 🇩🇪 Germany
Direct buses · no change
PragueBerounNurembergHeilbronn· 389 km as the crow flies
- 06:40 → 13:05FlixBus N1316Prague (Central Bus Station Florenc) → Heilbronn central train station · via Beroun, Nuremberg6h252 stopsRuns: Mon, Thu, Fri, Sat, SunThe night the clocks change (Sun 25 Oct: 05:40 → 12:05)Book on FlixBus ↗
- 15:10 → 21:30FlixBus N1315Prague (Central Bus Station Florenc) → Heilbronn central train station · via Plzeň, Nuremberg6h202 stopsRuns: DailyBook on FlixBus ↗
- 22:00 → 04:30+1FlixBus N168 ☾ OvernightPrague (Central Bus Station Florenc) → Heilbronn central train station · via Plzeň, Nuremberg6h304 stopsRuns: Thu to Sun (some weeks)The night the clocks change (Sat 24 Oct: 22:00 → 03:30+1)Book on FlixBus ↗
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Prague to Heilbronn?
Yes. 2.5 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Prague to Heilbronn?
The fastest takes 6h20; the slowest 6h30, for 389 km as the crow flies.
When do the buses leave?
The earliest leaves at 06:40 and the latest at 22:00, local time in Prague. Not every bus runs every day: pick a date above.
Is there a night bus from Prague to Heilbronn?
Yes: 1 overnight departure in the timetable, for example 22:00 arriving 04:30 the next morning.