Prague ▸ Leverkusen
Leverkusen ▸ Prague ⇄3.5 a dayfastest 11h15☾ 1 overnight busFlixBus🇨🇿 Czechia → 🇩🇪 Germany
Direct buses · no change
PragueDresdenChemnitzGeraJenaErfurtLeverkusen· 535 km as the crow flies
- 08:30 → 19:55FlixBus 020Prague (Central Bus Station Florenc) → Leverkusen (Mitte station) · via Dresden, Chemnitz, Gera, Jena…11h258 stopsRuns: Mon, Thu, Fri, Sat, Sun (some weeks)Book on FlixBus ↗
- 08:50 → 21:10FlixBus 084Prague (Central Bus Station Florenc) → Leverkusen (Mitte station) · via Nuremberg, Erlangen, Würzburg, Frankfurt…12h207 stopsRuns: Daily until Sat 14 Nov, not Tue 10 Nov, Wed 11 Nov, Thu 12 NovBook on FlixBus ↗
- 09:30 → 20:45FlixBus 264Prague (Central Bus Station Florenc) → Leverkusen (Mitte station) · via Dresden, Leipzig, Göttingen, Kassel…11h157 stopsRuns: Mon, Thu, Fri, Sat, Sun (some weeks)Book on FlixBus ↗
- 20:00 → 07:25+1FlixBus N23 ☾ OvernightPrague (Central Bus Station Florenc) → Leverkusen (Mitte station) · via Dresden, Leipzig, Halle, Dortmund…11h257 stopsRuns: Wed to Sun (some weeks)The night the clocks change (Sat 24 Oct: 20:00 → 06:25+1)Book on FlixBus ↗
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Prague to Leverkusen?
Yes. 3.5 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Prague to Leverkusen?
The fastest takes 11h15; the slowest 12h20, for 535 km as the crow flies.
When do the buses leave?
The earliest leaves at 08:30 and the latest at 20:00, local time in Prague. Not every bus runs every day: pick a date above.
Is there a night bus from Prague to Leverkusen?
Yes: 1 overnight departure in the timetable, for example 20:00 arriving 07:25 the next morning.