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Direct buses › From San Severo

San Severo ▸ Karlsruhe

Karlsruhe ▸ San Severo ⇄
1 a dayfastest 19h00☾ 1 overnight busFlixBus🇮🇹 Italy → 🇩🇪 Germany

Direct buses · no change

San SeveroPescaraAnconaRiminiBolognaMunichKarlsruhe· 979 km as the crow flies
  • 14:45 → 09:45+1
    FlixBus N422 ☾ Overnight
    San Severo → Karlsruhe central train station · via Pescara, Ancona, Rimini, Bologna…
    19h007 stops
    Runs: DailyThe night the clocks change (Sat 24 Oct: 14:45 → 08:45+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from San Severo to Karlsruhe?

Yes. 1 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from San Severo to Karlsruhe?

The fastest takes 19h00; the slowest 19h00, for 979 km as the crow flies.

Is there a night bus from San Severo to Karlsruhe?

Yes: 1 overnight departure in the timetable, for example 14:45 arriving 09:45 the next morning.

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