St. Gallen ▸ Prague
Prague ▸ St. Gallen ⇄Direct buses · no change
- 05:10 → 14:35FlixBus N106St. Gallen train station → Prague (Main Railway Station) · via Bregenz, Lindau, Memmingen, Munich9h254 stopsRuns: Mon, Tue, Wed, Sat, Sun (some weeks)Book on FlixBus ↗
- 21:50 → 06:25+1RegioJet ☾ OvernightSt. Gallen, Lagerstrasse → Prague, Hlavní nádraží · via Munich, Freising, Plzeň8h353 stopsRuns: Only Wed 18 Nov, Sat 21 Nov, Sun 22 Nov, Wed 25 NovBook on RegioJet ↗
- 21:50 → 06:28+1RegioJet ☾ OvernightSt. Gallen, Lagerstrasse → Prague, ÚAN Florenc · via Munich, Freising, Plzeň8h383 stops
- 21:50 → 06:30+1RegioJet ☾ OvernightSt. Gallen, Lagerstrasse → Prague, ÚAN Florenc · via Munich, Freising, Plzeň8h403 stopsRuns: Only Sat 31 Oct, Wed 4 Nov, Sat 7 Nov, Wed 11 Nov, Sat 14 NovBook on RegioJet ↗
Local times at each stop. Times from official open data: Czech national timetables (CIS JŘ) (file of 28 Oct 2026) and FlixBus (file of 25 Oct 2026). Checked Thu 29 Oct 2026; they cover 29 Oct to 25 Nov 2026. Timetables change, so check with the operator before you travel. A bus from a company that publishes no open timetable may be missing. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. Contains timetable data from CIS JŘ (Ministry of Transport of the Czech Republic). How we build this.
Quick answers
Is there a direct bus from St. Gallen to Prague?
Yes. 1.2 a day on average, with FlixBus and RegioJet, no change of bus (29 Oct to 25 Nov 2026).
How long is the bus from St. Gallen to Prague?
The fastest takes 8h35; the slowest 9h25, for 474 km as the crow flies.
When do the buses leave?
The earliest leaves at 05:10 and the latest at 21:50, local time in St. Gallen. Not every bus runs every day: pick a date above.
Is there a night bus from St. Gallen to Prague?
Yes: 3 overnight departures in the timetable, for example 21:50 arriving 06:25 the next morning.