Brussels ▸ Madrid
Madrid ▸ Brussels ⇄4 a weekfastest 21h55☾ 1 overnight busFlixBus🇧🇪 Belgium → 🇪🇸 Spain
Direct buses · no change
BrusselsParisPoitiersBordeauxSan SebastianBilbaoMadrid· 1,316 km as the crow flies
- 10:00 → 07:55+1FlixBus N1143 ☾ OvernightBrussels-North train station → Madrid (South Bus Station) · via Paris, Poitiers, Bordeaux, San Sebastian…21h556 stopsRuns: Daily until Tue 3 NovThe night the clocks change (Sat 24 Oct: 10:00 → 06:55+1)Book on FlixBus ↗
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Brussels to Madrid?
Yes. 4 a week on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Brussels to Madrid?
The fastest takes 21h55; the slowest 21h55, for 1,316 km as the crow flies.
Is there a night bus from Brussels to Madrid?
Yes: 1 overnight departure in the timetable, for example 10:00 arriving 07:55 the next morning.