Florence to Frankfurt bus: 1.6 a day, fastest 14h50

1.6 a dayfastest 14h50☾ 2 overnight busesFlixBus🇮🇹 Italy → 🇩🇪 Germany

Direct buses · no change

FlorenceBolognaMilanBregenzUlmStuttgartFrankfurt· 731 km as the crow flies

15:25 → 06:15⁺¹
FlixBus N537 ☾ Overnight
Florence (Villa Costanza) → Frankfurt central train station · via Bologna, Verona, Trento, Bolzano…
14h505 stops
Runs: Wed, Thu, Sat, SunThe night the clocks change (Sat 24 Oct: 15:25 → 05:15+1)Book on FlixBus ↗
20:00 → 13:30⁺¹
FlixBus N77 ☾ Overnight
Florence (Villa Costanza) → Frankfurt central train station · via Bologna, Milan, Bregenz, Ulm…
17h307 stops
Runs: DailyThe night the clocks change (Sat 24 Oct: 20:00 → 12:30+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Bus, train or plane

☾ Overnight: leave 15:25, arrive 06:15

The plane is 11h13 quicker door to door, but the night bus spends your night on the road instead of a day.

Bus · fastest direct15h43

To Florence (Villa Costanza)24 min
At the stop before departure15 min
FlixBus N53714h50
From Frankfurt central train station14 min

Plane · nonstop FLR to FRA4h30

To Florence (FLR)20 min
Check-in & security1h30
Flight FLR to FRA1h45
Landing to exit20 min
From FRA35 min

City centre to city centre. Getting to stops, stations and airports: typical public-transport times (estimates). Bus: be at the stop 15 min before. Plane: check-in and security 1h30 before, then getting out after landing; flight time typical for the distance.

Train instead?

No direct train from Florence to Frankfurt in pickthetrain's timetables: the bus is the no-change way.

Where Florence goes by direct train ↗

Flying instead?

2 airlines fly Florence to Frankfurt nonstop. Book on the airline's own site:

Air DolomitiFLR→FRABook direct ↗
Condor from 2027-05-06FLR→FRABook direct ↗

Compare on picktheflight ↗

Quick answers

Is there a direct bus from Florence to Frankfurt?

Yes. 1.6 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Florence to Frankfurt?

The fastest takes 14h50; the slowest 17h30, for 731 km as the crow flies.

When do the buses leave?

The earliest leaves at 15:25 and the latest at 20:00, local time in Florence. Not every bus runs every day: pick a date above.

Is there a night bus from Florence to Frankfurt?

Yes: 2 overnight departures in the timetable, for example 15:25 arriving 06:15 the next morning.

Florence ▸ Frankfurt

Direct buses · no change

Quick answers

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