Lugano ▸ Karlsruhe
Karlsruhe ▸ Lugano ⇄1.6 a dayfastest 6h50☾ 1 overnight busFlixBus🇨🇭 Switzerland → 🇩🇪 Germany
Direct buses · no change
LuganoZurichBaselFreiburgKarlsruhe· 336 km as the crow flies
- 12:40 → 21:00FlixBus 024Lugano (Via Ciani) → Karlsruhe central train station · via Zurich, Stuttgart8h204 stopsRuns: Mon, Thu, Fri, Sat, SunBook on FlixBus ↗
- 22:55 → 05:45+1FlixBus N474 ☾ OvernightLugano (Via Ciani) → Karlsruhe central train station · via Zurich, Basel, Freiburg6h503 stopsRuns: Mon, Thu, Fri, Sat, Sun (some weeks)The night the clocks change (Sat 24 Oct: 22:55 → 04:45+1)Book on FlixBus ↗
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Lugano to Karlsruhe?
Yes. 1.6 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Lugano to Karlsruhe?
The fastest takes 6h50; the slowest 8h20, for 336 km as the crow flies.
When do the buses leave?
The earliest leaves at 12:40 and the latest at 22:55, local time in Lugano. Not every bus runs every day: pick a date above.
Is there a night bus from Lugano to Karlsruhe?
Yes: 1 overnight departure in the timetable, for example 22:55 arriving 05:45 the next morning.