Mainz ▸ Zurich
Zurich ▸ Mainz ⇄6 a weekfastest 8h00FlixBus🇩🇪 Germany → 🇨🇭 Switzerland
Direct buses · no change
MainzFrankfurtHeidelbergKarlsruheFreiburgLörrachZurich· 291 km as the crow flies
- 07:10 → 15:10FlixBus 476Mainz central train station (exit West) → Zurich Bus Station · via Frankfurt, Heidelberg, Karlsruhe, Freiburg…8h008 stopsRuns: Mon, Tue, Fri, Sat, Sun (some weeks)Book on FlixBus ↗
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Mainz to Zurich?
Yes. 6 a week on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Mainz to Zurich?
The fastest takes 8h00; the slowest 8h00, for 291 km as the crow flies.
Is there a night bus from Mainz to Zurich?
Not an overnight one: every bus here travels by day or evening.